This week, we will discuss the final results of the NEFIGARD trial with the GFR slope data. Is targeted release budesonide aka Nefecon really a way to provide steroid efficacy without steroid side effects?
The PROTECT-V platform - RENALISM no more?
Dialysis dreams and sleepless realities: the SLEEP-HD trial
The SLEEP-HD Visual Abstract
Check out the dreamy Visual Abstract by Cristina Popa
Any sleep potion for insomnia in patients on hemodialysis?
🤔 E-alerts in AKI, the ELAIA-2 trial
A randomized clinical trial assessing the effect of automated medication-targeted alerts on acute kidney injury outcomes (Wilson, Nature Communications 2023)
🤔 RCT comparing Cefepime with Pip/Taz and AKI
Cefepime vs Piperacillin-Tazobactam in Adults Hospitalized With Acute Infection: The ACORN Randomized Clinical Trial (Quian, JAMA 2023)
🤔 Sparsentan in IgA Nephropathy
Efficacy and safety of sparsentan versus irbesartan in patients with IgA nephropathy (PROTECT): 2-year results from a randomised, active-controlled, phase 3 trial (Rovin, Lancet 2023)
Is Eculizumab a good Complement in STEC-HUS?
Two’s Company but Three maybe the Winner? Aldosterone Synthase Inhibition added to RASi + Flozin
ACE-ing the SPACE Trial: traversing the seas of RAS inhibition in non-cardiac surgery
Zibotentan and Flozins: Climbing to the ZENITH of nephroprotection?
Optimizing “Sparse” Treatments for FSGS
BEATing Calciphylaxis with an Adaptive Platform design
Unlocking the door to living kidney donor paradise?
This week, nephrologists hope they found the key to no-dialysis-land, where kindness and detailed, multistep interventions make the path to kidney transplant much easier. This was foreseen in our Freely Filtered episode and disputed during #KidneyWK 2023 late-breaking clinical trials session. Still, when it comes to RCTs’ results, will it be Deja Vu or a happy ending?
Salt-N-Water: PUSH it real good
HDF vs HD: Need for CONVINCE-ing Evidence
Giving oral bicarb raises serum bicarb
RCT of PO sodium bicarbonate in patients with renal transplant to see if impacts stability of renal function - catch up here!
