Time to vote for the Top Stories of 2025
Taking the reigns
In April 2014, Swapnil and I launched NephJC—and within weeks we were overwhelmed by the sheer work of running a twice-monthly, Twitter-based journal club. Fortunately, we also had a deep bench of friends on the internet. A rotating cast of brilliant volunteers stepped in, proving the old fortune-cookie wisdom true: many hands make light work.
Over the years, both Swap and I have taken on new responsibilities and new roles. Swap even has a big announcement on the horizon. As NephJC has grown, we’ve had to confront the hardest part of any grassroots digital project: succession. The good news is we’ve been spoiled with talent. Two exceptional leaders have been (not so) quietly steering the ship for the last 18–24 months, so much so that most of you won’t notice any change at all.
Today we’re making it official:
Your new Editors-in-Chief of NephJC are Brian Rifkin and Cristina Popa.
Both are highly decorated graduates from the NSMC. Brian won Rookie of the Year in 2021 and Cristina followed right behind him in 2022. She also tacked on the MVP award in 2024.
Swap and I will still be around, but less.
Dialysis deferred, logic recycled: BICAR ICU2
ORIGIN 3 interim-story: atacicept in IgAN
Check out ORIGIN 3 recap: a 36-week, interim analysis of phase 3 trial of atacicept in IgAN! Thread by NephJC intern Marc Soco.
Protein supplementation and quality of life
Do protein supplementation increase health-related QoL in advanced chronic kidney disease? Check out the recap thread made by NephJC intern Clemens Weber
Attacking the Origin of IgAN: ORIGIN3 and Atacicept
ORIGIN-3: The Visual Abstract
ORIGIN-3: El Resumen Visual
ORIGIN-3 ha llegado a NephJC con atacicept en NIgA.
Un paso sólido hacia una terapia dirigida anti BAFF/APRIL, que aborda la fisiopatología desde su origen. ¡Las señales tempranas son prometedoras!
Revisa el resumen visual realizado por Clemens Weber
Kidney Week in Houston: Day 3
Kidney Week in Houston: Day 2
Kidney Week in Houston: Day 1
Kidney Week Morning Run
2025 IgAN KDIGO guidelines: fresh out of press, already aging gracefully
KDIGO IgA Guidelines: A Patient Voice
KDIGO 2025 IgA guidelines - Visual Abstract
KDIGO 2025 is here. IgAN management is evolving with precision risk tools, new therapies, and a stronger focus on kidney protection.
Check out the visual abstract created by Natalia Nombera
Guías KDIGO 2025 IgA - El Resumen Visual
Las guías KDIGO 2025 están aquí. El manejo de la nefropatía por IgA (NIgA) está evolucionando con herramientas de estratificación de riesgo más precisas, nuevas terapias y un enfoque más sólido en la protección renal a lo largo de la vida.
Revisa el resumen visual creado por Natalia Nombera
Empagliflozin, the kidney, and what we still don’t understand
The Protein Pendulum in CKD: supplement or restrict?
Kidney transplant diaries: achieving immune tolerance by chimerism
A thread on the most relevant part of the chat on tolerance induction in HLA-matched transplant with donor hematopoietic stem cells (MDR-101). Thread by Akshaya Jayachandran.
