glomerulonephritis — Blog — NephJC

glomerulonephritis

Optimizing “Sparse” Treatments for FSGS

Optimizing “Sparse” Treatments for FSGS

This week, we will discuss sparsentan again, but this time in FSGS. This is the largest FSGS trial ever. Will endothelin antagonists crack the sclerotic FSGS segment?

Risk Stratifying A Heterogeneous Entity: IgA Nephropathy

Risk Stratifying A Heterogeneous Entity: IgA Nephropathy

This week, we will discuss a risk score which helps to prognosticate the most common glomerular disease. Not only is IgA most common - it is quite heterogeneous, which makes the problem of who should get treated quite difficult.

IgA Nephropathy: Testing Steroids Again

IgA Nephropathy: Testing Steroids Again

Stop-IgAN suggested steroids may not be useful in patients with intermediate range proteinuria. Now, in a different population with more proteinuria, TESTING finds a mixed result: some benfit + more adverse events. Should we keep on TESTING?