Episode 047: This is a guideline shredding study. This landmark study of blood pressure in pregnancy is going to change how we approach hypertension in pregnancy.
Freely Filtered does TESTING-2
Episode 048: TESTING is the latest IgA nephropathy trial and it is the comeback kid of nephrology trials. From a trial that was halted because of excess adverse events to a safe and effective therapy with just a few tweeks. Amazing turn around. Join the Filtrate as we put TESTING to the test with study author Sean Barbour.
Freely Filtered does SODIUM-HF
Episode 049: SODIUM-HF is the largest and longest RCT done looking at sodium restriction heart failure. The top line results show no effect but the more you look at the study the more problematic it is. The Filtrate take it to task.
Freely Filtered does The Classic Trial
Freely Filtered 050: CLASSIC Trial. The Filtrate look at the latest contribution to Fluid Wars, this one looking at late resuscitation.
Freely Filtered does Pip/Tazo and Vanco. Toxin or pseudotoxin?
The Filtrate looks at a trial that tries to dissect the bumps in creatinine we regularly see with Pip/Tazo. Is it AKI or pseudonephrotoxicity?
Freely Filtered does ADVOR
ADVOR turns the practice of sequential nephron blockade on its head by blocking the proximal tubule before the loop of Henle. Does it work? Join The Filtrate as we dissect the latest diuretic RCT.
Freely Filtered does EMPA-Kidney
Freely Filtered 054: EMPA-Kidney. EMPA-Kidney is the last of the big three to report their Kidney Endpoints SGLT2i trial (CREDENCE for Cana, DAPA-CKD for Dapa, and now EMPA-Kidney for Empa) and it answers some questions that had previously been unanswered. Join the Filtrate as they tear it apart.
Use @CaptainChloride's tweetorial to prep for tonight's NephJC
TESTING 2.0 in Kidney Medicine
The NephJC editorial in Kidney Medicine is live. Great work from Anand Chellapan and Rachael Kermond, supported by Tiffany, Jade and Swap. Read it here.
With a bonus table which already needs updating post EMPAKIDNEY!
The ANCA PLEX commentary on Kidney Medicine
The commentary on the BMJ meta-analysis on PLEX in ANCA vascuitis is now online on Kidney Medicine. Nice work by Anoushka Krishnan, Cristina Popa and Priyadarshini John. Read the paper here
Chronicles of Chronotherapy in Controlling Cardiovascular Complications
PATH-BP in Kidney Medicine
The #NephJC editorial on PATH-BP is now live on Kidney Medicine!
Nice work by Momen Abbasi, Priya John, Cristina Popa, helmed by Jade and Jamie.
TESTING 2.0 - The Visual Abstract
Check out the beautiful VA for TESTING trial by NSMC Intern Hamze Rage
The CHIP Visual Abstract
NSMC intern Mohamed Ibrahim created a beautiful visual abstract which simplifies the findings of CHIP study.
BASICS goes to Kidney Medicine
The discussion of the BASICS trial is up at Kidney Medicine. Great work by Mythri Shankar, Carlo Trinidad, and Elliot Tannor. Check it out here.
Diuretic Resistance: the Visual Abstract
This one is a difficult one. And Sophia Ambruso had created a nice one for NephMadness - so why mess with such a nice piece of work? Here it is:
The Path BP Visual Abstract
Excellent visual abstract from Husam Alzayer, NSMC intern of the class of 2022
Xenotransplants: The Visual Abstract
The visual abstract for the xenotransplant case report, from Namrata Parikh
Timing Dialysis Right: The Visual Abstract
Created in a time crunch, the visual abstract for this week’s study from Elena Cervantes:
AURORA goes to Kidney Medicine
AURORA-1, the placebo controlled RCT of voclosporin in lupus nephritis is another NephJC discussion that is now available as a Kidney Medicine manuscript. Bourne Auguste, Jade Teakell, and Avinash Rao Ullur did a great job on this. Take a look.